Introduction

It is non-immunogenic, semitransparent cover, which seals the would while breathing like skin, thereby healing without scar formation. Bovine achilles tendon is solubilised by mechanical, enzymatic and chemical treatment and the pure soluble collagen is purified by successive precipitations at acidic / alkalinne pH. The pure soluble collagen is cut into sheets, cross linked with UV/GTA and sterilised after dry packaging. Unlike collagen sheet, it sticks over the wounds very easily, whereby the progress of would healing can be monitored easily from outside because of the semi-transparent nature of the sheet.

Industry classification

Primary : Slaughter house / animal byproducts
Secondary : Drug / pharmaceutical industry
Product type :Commercial

Manufacturing

a) process used

Primary : Biochemical processing
Secondary : Sterilisation and ampouling

b) Major machinery used : Acid and alkali resistant vessel, shakers, homogeniser, ethylene oxide chambers, quality control lab, laminar flow chamber, UV sterilisation chamber, dies for cutting sheets, dry / blister packaging equipment.

Status :Licensed

i) Year first Licensed : 1999
ii) No. Of License : One (M/s. Eucare Pharmaceuticals Pvt. Ltd., Chennai)
iii) Whether in Production : Sample production is in progress

Economic Information:

Minimum Economic size: 5000 sheets per month (size 10x10cm2)
Optimum Investment : Rs.50 lakhs (approx.)

Major Raw Materials Required : Bovine skin, achilles tendon, proteolytic enzymes, acid, alkali, ethylene oxide

Patent Information

If Patented : Indian patent applied for
Patent No. : Appl. No.1351 DEL99
Country : India
Date granted : Patent Pending

Contact for more information:

Director,
Central Leather Research Institute (CLRI),
Chennai -600 020, India