Versatile
Disposable FET-Based Biosensors
Description
Conventional CHEMFETs (chemical field
effect transistors) are silicon MOSFETs with the gate uncovered
to make it chemically sensitive. These gates, made of poly-silicon
or metal which are replaced with a chemically sensitive metal,
are widely used but are not very effective. Furthermore, due
to inefficiencies in removing trapped charges/dipoles after
a sensing event, CHEMFET sensors experience a lot of drift
in their characteristics with regard to time.
The key difference
from established silicon CHEMFET technology is that CHEMFETs
use channel charge modulation by dipoles (which have a net
charge of zero), whereas in our device we use trapped positive
charges, which produce a much greater conductivity modulation.
This results in a performance improvement of a factor of 10X
to 100X in comparison with existing technology (tested with
air-based analytes). A similar increase in sensitivity is
expected to be obtained in other media as well. The invention
covers inorganic-inorganic four-terminal devices for vapor/gas
sensing, as well as inorganic-inorganic four-terminal devices
for sensing in aqueous ambients
Benefits
- Outperforms traditional CHEMFETs by
a factor of 10 in terms of magnitude of response
- Observed response in the chemical memory
mode 10 to 100 times more intense
- Can run the sensor in many modes, multiparameter
(3-in-1 sensor)
- Based on established technology
- Low cost, disposable, and easy to manufacture
(combined with thin film technology)
- Suitable for various ambients
- Can be integrated at a system
level for RFID applications
Features
- Given its advantages, this technology
can still function as a traditional CHEMFET.
- The sensors can be refreshed after
a sensing event.
- The unique sensing mode "both
on" appears to be the most sensitive of all the multiple
sensing mechanisms present.
Market Potential/Applications
Water testing, water quality monitoring, glucose level testing,
lactic acid level monitoring, disease detection and diagnostics,
and various industrial uses
Contact:
University of Texas,
Austin, USA
Website : www.otc.utexas.edu

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