Live
Attenuated PPR Vaccine
Introduction
An Indian R&D organization offers technology of live
attenuated Peste des Petits ruminants (PPR) vaccine.
PPR is an acute, highly contagious and fatal rinderpest-like
disease of small ruminants, and in unprotected animals the
mortality may reach 60-70%. The PPR virus was first reported
in India in 1987, during an outbreak in Tamil Nadu, and since
then, the disease was reported from all over the country.
The use of the rinderpest vaccine to protect small ruminants
against PPR is contraindicated because its use induces antibodies
to rinderpest, which compromises sero-surveillance for rinderpest.
Hence, the present vaccine was developed for the control of
PPR in sheep and goats. It is used for prophylatic vaccination
against PPR in sheep and goats.
Area of Application: Pharmaceutical
industry; and Veterinary medicine.
Advantages
The freeze-dried vaccine should be stored and transported
at 2-8oC. The vaccine diluent should be tored in a cool and
dark place. The chilled diluent (4oC) should be used for reconstituting
the vaccine. For administering the dose, transfer a small
aliquot of diluent from the 50 ml bottle provided (phosphate
buffered saline) to the vial containing the freezedried vaccine,
and mix well to ensure uniform suspension.
Then, transfer the suspension to the corresponding diluent
vial and mix well. Once mixed, 1 ml of the reconstituted vaccine
is injected into one sheep or goat subcutaneously. Only sterile
syringes and needles should be used.
Transfer Forms:
Know-how; Manufacturing licence; and Training.
Contact
Asian and Pacific Centre for Transfer of Technology,
APCTT Building,
C-2 Qutab Institutional Area,
P.O.Box - 4575
New Delhi - 110 016
India

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