Introduction

The Central Council for Ayurveda & Siddha, under Ministry of Health & Family Welfare has developed the the technology for above preparation. A herbal compound consists of Brahmi(Centella asiatica), Vacha(Acorus calamus) Sarpagandha(Rauwolfia serpentina), Kusta(Saussurea lappa) Tagar (Nymphoidi macrospermum) and Jatamansi (Nardostachys jatamansi)

Psychosis is the most elaborately dealt in Ayurveda. It is described to be caused on account of unwholesome food and improper physho-behavioural activities, which impair the three Dosa viz; Vata, Pitta and Kapha. In Unmada, Manas or Mansadosa viz. Rajas and Tamas are also affected. Hence treatment to restore Tridosa imbalance should be coupled with correction of Mansadosa. It is rightly defined as a Manasavikara caused due to the vitiated Saririka and Manasadosas with a mounting upward pressure and manifesting as the unsettled condition of the Manas (mind), along with the impairment of other seven factors described earlier.

Clinical Trials

Clinical trial was conducted using Brahmayadiyoga. Significant improvement was observed. The results are comparable with modern control chlorpromazine. Controlled studies were conducted in acute schizophrenics, chronic schizophrenics and acutely ill patients with different types of schizophrenia using Brahmyadiyoga and Tagara. These studies were done in association with the Department of Psychiatry, NIMHANS, Bangalore with Brahmydiyoga..

Process

Powder the above materials to 100 mesh powder in the prescribed proportion alongwith some additives like starch, gum acacia, etc. and sodium benzoate. Powder & additives are fed into a ball mill for uniform mixing and fine grinding. The mass is then granulated. The granules are dried at 70oC in a hot air drier. The granules of the desired size are fed to a heavy duty tablets making machine. The tablets are strip packed to protect them from the atmospheric moisture.

Plant Parameters

Capacity (Tablet / Year) : 10 million

No.of Shifts : / day 2

Working days: / Yr 300

Land Area,: m2 600

Covered Area, : m2 200

Manpower

Managerial : 1
Skilled : 5
Unskilled : 10

Plant& Machinery

Pulveriser : Ball mill

Evaporating pans : Extractor

Mixing machine : Granulator

Economics

Plant & Machinery : Rs. 20,00,000

Know-how Fees : Rs. 3,00,000

Recurring Royalty : 4 % on sales

Licence Period : 10 Years

Nature of Licence : Non exclusive

*The above figures are for budgetary purposes only and subject to change in subsequent offers

Contact

Asian and Pacific Centre for Transfer of Technology,
APCTT Building,
C-2 Qutab Institutional Area,
P.O.Box - 4575
New Delhi - 110 016
India