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A Simple Process for Asarone free
Acorus Calamus Oil
Details of present/Existing Technology.
Shortfall / Technological gaps in the existing technology
Acorus calamus L. (family Araceae) is a
well known medicinal plant. Its essential oil is being used
for many years by perfumery and pharmaceutical industries.
However, its oil has now been prohibited in flavour, perfumery
and pharmaceutical industries due to high percentage of toxic
beta-asarone present mainly in tetraploid and hexaploid strains
of Acorus calamus found mostly in the Asian belt. However,
separation ofb -asarone from calamus rhizomes (americanus
var.) by supercritical extraction or by raising plants on
alkaline soil has been developed but these methods have not
lowered the percentage of high beta-asarone (70 to 90%) found
in tetraploid and hexaploid varieties
Approach
adopted in new technology to evade technological gap in the
exiting one
A simple chemical process has been developed
to make asarone free calamus oil.
Advantages
There are
several benefits such as (a) economical gain for calamus oil
of tetraploid and hexaploid strains (b) asarone free calamus
oil has sweet, spicy and fruity smell which can be used in
the area of flavour and pharmaceutical industries.
Brief Description
Acorus calamus (family : Araceae) commonly
known as "sweet flag", is a perennial plant. It
grows worldwide wildly along swamps, rivers and lakes. It
is also cultivated in many countries because of demand of
its essential oil in flavour, perfumery and pharmaceutical
industries. However, Acorus calamus oil, obtained from tetraploid
and hexaploid strains (distributed extensively in Asian countries)
has been recently proved to be toxic and carcinogenic due
to beta-asarone. As a result, calamus oil produced in India,
Nepal, Pakistan, Japan and China where percentage of beta-asarone
is in the range of 70 to 90% has diminished the market potential
of this oil while calamus produced from diploid strains in
North America are asarone free. Similarly, calamus produced
from triploid strains in Europe contain beta-asarone upto
8%, therefore, diploid and triploid strains are still allowed
for clinical effectiveness and safety. To solve the problem
of beta-asarone in calamus oil of tetraploid and hexaploid
strains, a simple technology is urgently needed.
Applications
Food and Pharmaceutical industries
Flavour, perfumery and pharmaceutical industries
Patenting Details:
A patent on asarone free oil has been filed in USA (patent
No. 09/652, 376 filed on Aug. 31, 2000)
Technology Transfer Assistance Offered:
Know-how
Contact for more information:
Director
Institute of Himalayan Bioresource Technology
Post Box No.6 Palampur
Himachal Pradesh - 176 061
India

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