Natural and Herbal
Medicine - Purchase
the Eucommia ulmoides Leaf extract --Mary Liu is
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Description:
Eucommia ulmoides Leaf extract Tochu
tea Polyphenols Eucommia ulmoides Leaf extract Tochu
tea Polyphenols The suppressing effect of crude extracts
of Tochu tea, an aqueous extract of Eucommia ulmoides
leaves and a popular beverage in Japan, on the induction
of chromosome aberrations in CHO cells and mice was
studied. When CHO cells were treated with Tochu tea
crude extract after MMC treatment, the frequency of
chromosome aberrations was reduced. Out of 17 Tochu
tea components, 5 irridoids (geniposidic acid, geniposide,
asperulosidic acid, deacetyl asperulosidic acid, and
asperuloside) and 3 phenols (pyrogallol, protocatechuic
acid, and p-trans-coumaric acid) were found to have
anticlastogenic activity. Since the anticlastogenic
irridoids had an alpha-unsaturated carbonyl group, this
structure was considered to play an important role in
the anticlastogenicity. The anticlastogenic effect of
Tochu tea extracts was examined in mice using a micronucleus
assay. When mice received 1.0 ml 4% Tochu tea extract
by oral gavage 6 h before intraperitoneal injection
of MMC, a decrease in the frequency of micronuclei was
observed. This decrease was not due to a delay in the
maturation of micronucleated reticulocytes Your early
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Contact:
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