Biochemical and Biotechnology
- Enzymatic Synthesis of Glyco-Conjugates
Introduction
Glyco - conjugates are molecules in which sugars are
linked to amines, alkyl and protein molecules. Many
of these are biologically important as cell surface
receptors, as molecules involved in cell - cell recognition,
cell - drug recognition processes. Enzymatic synthesis
of these special molecules provides alternative routes
to conventional medicine. We have shown applications
of a new recombinant E. coli expressed b-glucosidase
in the synthesis of these of these molecules. Many novel
oligosaccharides, alkyl glucosides of commercial importance
have been synthesised using this enzyme under laboratory
conditions.
Special Features:Special
compounds (carbohydrates) can be synthesised using this
enzyme.
Glossary:
Glyco conjugates:molecules in which sugars are linked
with amine alkyl or protein group
Contact:
The Director
Foundation for Innovation and Technology Transfer
Indian Institute of Technology Delhi
Hauz Khas, New Delhi-110016
Tel : 91-011-26597167, 26857762, 26581013
Fax : 91-011-26851169
E-mail : mdfitt@gmail.com
